Microbiology
IMMUNOBIOLOGY OF BACTERIAL CPG-DNA
ISBN : 9783540664000
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Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book reviews the data emerging in this field.
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Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book reviews the data emerging in this field.
Specifications
| Author | WAGNER |
| Edition | CURRENT EDITION |
| Year | 2000 |
| Publisher | SPRINGER NATURE GROUP |
| Binding | HARDCOVER |
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